Dietary supplement made from plant extracts, particularly Taraxacum Officinalis, Milk Thistle, Artichoke and Berberis Vulgaris, combined to support the natural functions of the liver.

…however, supplementation with phytoextracts with a depurative,
choleretic and cholagogue action is recommended…²

KEY BENEFITS

The Patented Spagyric Process

enhances the effectiveness of phytoextracts through a unique method of

separation – ENHANCEMENT – RECOMBINATION

of plant actives.

35% of the adult population has a form of non-alcoholic fatty liver disease (NAFLD).
Non-Alcoholic Fatty Liver Disease (NAFLD) is a hepatic manifestation of metabolic disorders and includes various stages of liver diseases, ranging from steatosis to liver cirrhosis.
Epavin is a dietary supplement that supports and aids in the treatment of the early stages of fatty liver disease of dietary, metabolic, and iatrogenic origin.

SPAGYRIC PLANT EXTRACTS

Milk Thistle

Stabilizes liver cell membranes

Protects against toxic agents

Stimulates hepatocyte protein synthesis

Taraxacum officinalis

Stimulates renal receptors

Promotes bile acid secretion (choleretic effect)

Supports lipid digestion

Berberis vulgaris

Supports metabolic regulation

Enhances glucose uptake and helps reduce blood sugar levels

Alters bacterial membranes for antimicrobial support

Artichoke

Increases bile flow (choleretic action)

Helps reduce endogenous cholesterol by inhibiting the HMG-CoA reductase enzyme

10 FUNCTIONAL PHYTOEXTRACTS
FROM SPAGYRIC MOTHER TINCTURES
in UNIQUE FORMULATION³

Promotes healthy liver function
Enhances the effectiveness of metabolic therapies
Aids multiple digestive processes
Provides chelating action against heavy metals⁷

The chelating action of EPAVIN on heavy metals—specifically cadmium, mercury, and lead—as well as its antioxidant activity, has been demonstrated in an in vitro study on liver cells conducted by the Department of Pharmacy and Pharmaceutical Sciences at the University of Bari “Aldo Moro.”
The study, conducted on HepG2 cells, examined the protective effect of the EPAVIN supplement against the toxicity of heavy metals (Cd²⁺, Hg²⁺, Pb²⁺). Under normal conditions, HepG2 cells maintain an epithelial morphology; however, exposure to heavy metals caused significant alterations, including loss of cell adhesion and changes in cell shape and size. Treatment with EPAVIN, even at low concentrations (500 µg/ml), preserved the physiological morphology of the cells, suggesting that EPAVIN offers protection against morphological damage, likely due to its antioxidant properties.

CTRL

Epavin 500 μg/mL

Cd2+ 30 μM

Epavin 500 μg/mL
+
Cd2+ 30 μM

Hg2+ 30 μM

Epavin 500 μg/mL
+
Hg2+ 30 μM

Pb2+ 30 μM

Epavin 500 μg/mL
+
Pb2+ 30 μM

THE ADVANTAGES
OF THE DROPLET FORMULATION:

Higher bioavailability Better patient compliance 10 enhanced active ingredients from the spagyric method

HOW TO USE

30 drops 2 times a day (1/2 pipette = 30 drops)

WARNINGS

Do not use during pregnancy or breastfeeding

NUTRITIONAL INFORMATION
Average content of
key ingredients		 Per maximum daily dose (60 drops = 2 ml)
Taraxacum officinalis EI 0.25 ml
Milk Thistle fruit EI 0.25 ml
Artichoke leaves EI 0.25 ml
Barberry bark EI 0.25 ml
Boldo leaves EI 0.2 ml
Black Radish EI 0.2 ml
Rhubarb root EI 0.2 ml
Chrysanthemum aerial parts EI 0.2 ml
Desmodium leaves EI 0.1 ml
Combreto leaves EI 0.1 ml
Peppermint 0.02 ml
Rosemary EO 0.02 ml

PRODUCT ALCOHOL-FREE IN DILUTION:
25 drops in half a glass of water as per test report 23/000389151

SCIENTIFIC BIBLIOGRAPHY: ▸

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